Peptides are isolated using phage display against TNF alpha and TNFR2, and then tested for anti-inflammatory properties in the planned vascular models. The vascular models should be suitable for high-throughput screening (HTS) and provide a basis for the development of specialist detection modules by Beckman Coulter. Further tests on the isolated peptides were carried out by the industry partner. The data from the project will be used for the construction of prototype modules for the HTS market, and the peptides produced by the screening are expected to be further commercialised in follow-up projects.
The project was funded by the Austrian Research Promotion Agency under the BRIDGE programme.